MEDICAL CONDITIONS

Alzheimer’s

Alzheimer's
Written by Elena E.

CBD in the case of Alzheimer’s Disease – A Natural Form of Therapy

You forget where the key is, look for your sunglasses, whilst in the worst case still wearing them on your head, or occasionally forget the name of a relative. There is no immediate need to worry as not all cognitive absent-mindedness is a sign of Alzheimer’s disease. Nevertheless, the onset of dementia becomes gradually noticeable. At the beginning it is just small cases of forgetfulness which, as the disease progresses, lead to changes in personality and behaviour.

Alzheimer’s disease is widespread within society. There is still no treatment to cure the disease in prospect. Even if therapies and medication can relieve symptoms, the disease itself cannot be cured. Using CBD in the case of Alzheimer’s is a subject which has arisen repeatedly in recent times. As studies have shown, cannabidiols may very well delay the progress of Alzheimer’s and help those affected to enjoy a better quality of life.

Alzheimer’s – Where does the disease come from?

Dementia negatively affects more than 35 million people worldwide. One of the most common forms of this illness is Alzheimer’s disease (AD). The causes of this neurodegenerative disease are disputed and even today not fully explained, yet Alzheimer’s is often attributed to genetics, infections of the nerve tissue and /or deposits in the brain. In the case of the latter, the following occurs in the body: the body’s own cells are shut down in the brain by deposits of so-called senile plaque. These paralysed cells are prevented from forwarding information to the nervous system.

All previously examined causes of Alzheimer’s disease lead to loss of memory and behavioural change. The symptoms of Alzheimer’s are above all characterised by cognitive impairments. Initially, the short-term memory is impacted by the disease and later the long-term memory. The degeneration of the brain cells causes feelings of depression, states of aggression and psychosis. There is a lack of drive and the sufferer withdraws into him/herself.

Alzheimer

Difficulties in concentrating and a reduced ability to make judgements through to degraded linguistic expression are stages in the symptoms of Alzheimer’s disease. The behavioural and personality disorders lead in the worst case to a complete lack of orientation. The person affected is no longer able to lead an independent life.

Conventional Therapy Measures – Can Alzheimer’s be cured?

The clear answer from science: No. Alzheimer’s as a disease cannot be cured. Nevertheless, some therapeutic measures promise success in containing the symptoms and delaying the progression of the disease. It is not too often that you read in scientific articles that the disease cannot be stopped but the symptoms can be contained. This is where CBD can help in the case of Alzheimer’s disease.

In conventional medicine, a distinction is usually made between therapy with drugs and non-drug therapy.

In Alzheimer’s medicine, cholinsterase inhibitors or memantine are usually used to stop the disease. These are intended to prompt the neurotransmitters in the brain to return to normal behaviour. It is known that this therapy only has a latent effect.

Antidementia, antidepressants and neuroleptics are believed to delay the onset of the disease and alleviate symptoms in patients with Alzheimer’s disease. However, the different drugs used in conventional medicine have varying side effects. For example, neuroleptics may improve conspicuous behavioural patterns and curb aggressiveness, sleep disorders and delusions, but they also lead to a deterioration in cognitive performance. A natural variant of Alzheimer’s drugs exists in the form of Ginkgo Biloba. There are indications that the extract of the Ginkgo tree improves the ability to think and remember.

Alzheimer symptoms can be counteracted with non-drug treatment therapies. It is important to strengthen the patient’s everyday routine, to use the sensory organs and to train the memory. Various forms of therapy are currently open to Alzheimer’s disease. Cognitive training, memory exercises, physio-, ergo- and behavioural therapies are where the main focus lies.

CBD in the case of Alzheimer’s disease – How does cannabidiol affect the course of the disease?

CBD plays a positive role in different stages of Alzheimer’s disease. We already know today that natural CBD can have a neuronal stimulating, antioxidative and anti-inflammatory effect. If the correct dosage is taken, there are no side effects.

  • 1. CBD oil is no panacea but it can certainly help!

    Cannabis and CBD surely are no panaceas but for many people it is a natural remedy that can help with more than 65 different medical conditions. CBD is still quite unexplored but many scientists, doctors and pharmacists shed their prejudices and are interested in the health benefits of cannabidiol. Just always remember: CBD CAN be helpful - but it isn't always.

    cbd-no-panacea-help
  • 2) CBD addresses the endocannabinoid system

    Pretty much nobody uses CBD without a reason to do so. CBD is a cannabinoid which is a group of substances that can naturally be found in various plants. These cannabinoids address the endocannabinoid system. Every human has such a system. Via various receptors within this system a number of functions in the body can be regulated, renewed or fixed.

    endocannabinoidsystem
  • 3) Breast milk contains CBD

    A study in 2017 has shown that cannabinoids are not only natural components of cannabis but can also be found in breast milk. Cannabinoids are not only valuable for the neurological growth phases but have many other astonishing health benefits. Without cannabinoids in breast milk newborns would would be less hungry and therefore drink less.

  • 4) CBD is the allrounder amongst cannabinoids

    Every cannabinoid has its own effects. Nonetheless, CBD can be called the allrounder among all cannabinoids. It is not only anti-inflammatory but can also slow down growth of diseased cells. It is also anxiolytic and an immunosuppressant. Therefore, CBD makes for a great dietary supplement and should always be the base. You can add more cannabinoids by choosing full-spectrum CBD products.

  • 5) CBD does not get you stoned

    Cannabidiol is the so-called antagonist of THC. THC means Tetrahydrocannabinol. It is psychoactive and can be found in certain cannabis strains. CBD counteracts with the part of THC that gets consumers 'stoned'. Therefore, the very small amount of THC that can be found in many CBD products is kind of neutralized by the CBD. As a result, CBD products are totally legal and non-psychoactive.

  • 6) WHO rates CBD as harmless

    The World Health Organization WHO published a 27 pages long report where they classify CBD as harmless. The organization states that pure CBD and products that contain less than 0.2% THC are in no way taken into the drug conventions. A reason for that is that CBD is not predicating and there is no danger of abuse. Therefore, CBD is as harmless as water.

  • 7) CBD is not a doping substance and is used in professional sports

    CBD can help reduce inflammations and can support regeneration after physical activities. As a result, many professional athletes (especially in the US) in football, basketball or martial arts use CBD. Many famous athletes also advertise respective compounds. In August 2019 UFC champion Nate Diaz caused a lot of furore when he smoked a CBD joint before a big fight. Nonetheless, it was totally legal since CBD is specifically excluded from the WADA doping list.

    cbd-not-a-doping-substance-is-used-in-sport
  • 8) CBD can be prescribed

    In conventional medicine cannabidiol is not very popular yet. First, doctors need to be informed about CBD in order to shed their prejudices and gather experiences. Nonetheless, even nowadays there are numerous specialists and general practitioners who have trust in the medical potential of cannabis. In some cases doctors also prescribe CBD to their patients.

  • 9) CBD and cannabis can help to cleanse the environment

    Cannabis is a plant that can naturally grow almost everywhere in the world. Additionally, it consumes up to four times as much CO2 as trees. Cannabis is also known for absorbing toxic substances and radioactive chemicals from the soil. Therefore, cannabis is able to cleanse the environment und is good for the earth's climate.

    https://pixabay.com/de/photos/hanfpflanze-hand-cannabis-sativa-3661210/
  • 10) CBD exists in all kinds of shapes

    Most people know CBD in the shape of CBD oil. CBD oil is so popular because it is easy to dispense and is well absorbed by the body. Nonetheless, there are numerous other kinds of CBD products such as e-liquids, salves, creams, pastes, flowers, sweets, food or crystals. On CannaTrust.uk you can find many of these products!

CBD as a neural stimulant

In recent years, the role of the endocannabinoid system (ECS) in neurodegenerative diseases such as Alzheimer’s has been studied. The CB1 receptor, one of the two most important endocannabinoid receptors, is represented in those regions of the brain that are responsible for memory and learning. This is where a bridge can be built between CBD and Alzheimer’s, because CBD docks at the CB1 receptor.

The herbal cannabinoids activate the CB1 receptor, in the same way as the endogenous cannabinoids in the body. This mediates the effect of cannabinoids in the central nervous system. CBD, which is exogenously supplied by the hemp plant, may therefore help to delay the onset of neurological diseases and thereby have a positive influence on the complex nervous system. 

The stimulation of nerve tissue by CBD in the case of Alzheimer’s disease can help to reduce certain symptoms. CBD can thus be considered a neuronal stimulant.

CBD as an antioxidant

CBD in Alzheimer’s disease is also seen as providing antioxidant cell protection. Oxidation in the body provides energy, which is responsible for our well-being and survival. Oxidative stress, on the other hand, reduces this process and leads to immuno-inflammations.

As a result, the antioxidant capacity of the body’s own cells is impaired and free radicals are released. Synapses and neurons are lost. Among other things, oxidative stress is associated with Alzheimer’s disease.

There are some helpful methods to counteract the increased formation of free radicals in our body. In addition to proper nutrition, CBD is considered an antioxidant. It can slow down the process of oxidative stress and relieve neurological symptoms. The antioxidant properties of cannabidiol (CBD) have already been investigated in studies. Positive results can be reported. However, when using CBD as an antioxidant, care should be taken to use the correct dosage. Too many antioxidants in the body could have a negative effect.

CBD as anti-inflammatory agent 

CBD has been shown to have an anti-inflammatory effect in various studies. Neurodegenerative diseases such as Alzheimer’s usually lead to inflammation of the nerve tissue. In addition, a study by the DGN (German Society of Neurology) has found out that inflammation of the brain is not only an attendant symptom of Alzheimer’s. The inflammatory processes even contribute to the progression of neurodegeneration. The anti-inflammatory effect of CBD can be helpful against these infections and thus delay the growth of the disease.

CBD has also been shown to have further positive benefits in Alzheimer’s patients with aggression, loss of appetite, sleep disorders and other behavioural problems. Since it is generally considered to be calming, positively enriches the mood of the users and helps to relieve anxiety and pain, CBD can be a beneficial remedy of choice for Alzheimer’s disease.

Alzheimer’s and CBD – An outlook

A study from 2016 can be considered a possible pioneer for the use of CBD in the treatment of Alzheimer’s disease: In 10 Alzheimer’s patients, the consumption of CBD was shown to bring about a significant reduction of the NPI (neuro-psychiatric inventory value), from 44.3 to 12.9 after only 4 weeks. The remarkable decrease in behavioural disorders such as aggression, agitation, delusion, apathy and irritability, prompted an extensive clinical study.

Numerous studies are currently investigating the positive effect of CBD in the fight against Alzheimer’s disease. Increasingly, this scientific research points towards a beneficial response.

Conclusion


  • CBD can be used both to delay the disease and as a remedy against the symptoms.

Further studies

https://www.ncbi.nlm.nih.gov/pubmed/26271310

https://www.ncbi.nlm.nih.gov/pubmed/22448595

https://www.ncbi.nlm.nih.gov/pubmed/24256258

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562334/

https://www.ncbi.nlm.nih.gov/pubmed/15030397

https://www.ncbi.nlm.nih.gov/pubmed/25024327

https://www.ncbi.nlm.nih.gov/pubmed/25147120

https://www.ncbi.nlm.nih.gov/pubmed/19370677

https://www.ncbi.nlm.nih.gov/pubmed/17592514

https://www.ncbi.nlm.nih.gov/pubmed/19228180

https://www.ncbi.nlm.nih.gov/pubmed/?term=Cannabinoid+receptor+1+deficiency+in+a+mouse+model+of+Alzheimer%E2%80%99s+disease+leads+to+enhanced+cognitive+impairment+despite+of+a+reduction+in+amyloid+deposition

https://www.ncbi.nlm.nih.gov/pubmed/18781980

https://www.ncbi.nlm.nih.gov/pubmed/21639405

https://www.ncbi.nlm.nih.gov/pubmed/19370677

https://www.ncbi.nlm.nih.gov/pubmed/24288245

https://www.ncbi.nlm.nih.gov/pubmed/24634659

http://www.nextavenue.org/article/2012-10/can-marijuana-save-aging-brain

https://www.ncbi.nlm.nih.gov/pubmed/26757043

https://www.ncbi.nlm.nih.gov/pubmed/26271310

https://www.ncbi.nlm.nih.gov/pubmed/27110749

https://www.ncbi.nlm.nih.gov/pubmed/27567873

http://www.mdpi.com/1422-0067/18/1/26

https://www.ncbi.nlm.nih.gov/pubmed/28217094

https://www.ncbi.nlm.nih.gov/pubmed/28412918

When taking products containing cannabinoids, interactions with various drugs may occur under certain circumstances. If you are taking medication yourself, then the use of CBD and other cannabinoids must first be discussed with the treating physician.

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About the author

Elena E.

Elena E.